Dr Jill Stocks PhD
Core Research Fellow
- Email: firstname.lastname@example.org
- Telephone: +44 (0)161 3067390
Core research fellow: Greater Manchester Patient Safety Translational Research Centre
Responsibilities include analysis of primary care data and evaluation of public patient involvement in primary care research.
- medication safety
- evaluation of interventions (natural experiments)
- trends and impact of interventions in occupational health
- safety in primary care
- public and patient involvement in research
- hand hygiene and skin care in healthcare workers
- Competent in several statistical techniques including multilevel regression modeling, population standardization and SMRs, odds ratios, statistical testing and constructing confidence intervals, specificity and sensitivity analysis, survival analysis, power calculations.
- Designing, maintaining and cleaning databases, including data security and compliance with the Data Protection Act.
- Experienced in the design, implementation and analysis of RCTs, cross-sectional, case-control, longitudinal and cohort studies.
- Use of Microsoft Access, Excel, ARC Gis, Stats Direct, SPSS and Stata.
- Writing papers grant applications, ethics applications and reports.
- Design and analysis of questionnaires, including administering phone or face to face interviews.
- Extracted data from medical records (PCTs and NHS).
- Undertaken systematic literature searches and reviews.
- Organised the routine aspects of RCTs eg Steering Committees, Data monitoring Committees, randomization schedules etc
- Regularly used government statistics such as ONS, NHS, HSE, HPA and DEFRA data.
- Recruiting and maintaining participation in difficult groups e.g. infertility patients.
- Working with clinicians with minimal time to devote to research.
- Supervised research nurses and physiotherapists working on research projects.
- Monoclonal and polyclonal antibody production and purification including fusion with polyethylene glycol; selection, freezing and thawing of hybridomas; adaptation to serum free medium; using proteins and haptens to raise polyclonal antibodies in animals and large scale production of monoclonal antibodies by cell culture. Culture of other mammalian cell lines.
- Protein purification and characterisation techniques including FPLC; gel-filtration, ion-exchange and affinity chromatography; ultrafiltration; ELISA; RIA; ELRA;Western blot; Southern blot, SDS-PAGE; fluorescent and uv/vis spectrophotometry; antibody fragmentation and separation of the fragments.
- Protein derivatisation with polyethylene glycol, dyes, biotin, acrylamide by means of redox polymerization of protein primary amines, cyanogen bromide and haptenisation. Assays to assess the extent of derivatisation such as primary amine estimation or various other amino acid analyses.
- Radiolabeling of proteins and cells including iodination of proteins and the labeling of cells with iodine, chromium, tritium and carbon, cell impedance counting, fluorescent labeling of cells and proteins, use of the avidin-biotin interaction. Binding assays and construction of Scatchard plots.
- DNA extraction and quantification, surface plasmon resonance
- Partitioning in two phase aqueous polymer systems as a means of separating proteins and cells on the basis of their surface chemistry, eg. antigenic differences, and the use of a counter-current distribution apparatus.
- HPLC analysis of anthracycline derivatives, chlorambucil, and pH-sensitive dyes in order to measure cellular uptake or intracellular pH. HPLC separation of DNA adducts. Dose-dependent and pH-dependent cytotoxicity assays using cultured cells.
Supervisor for PhD and MSc students
Tutor for Professional and Personal Development (1st & 2nd year medical students)
Jill’s main interest is in epidemiological methods and she is experienced in analysing routine healthcare and surveillance data. Recently she has been looking at prescribing safety using the Clinical Practice Research Datalink. Prior to this she worked on evaluating the impact of national or international interventions through occupational disease surveillance and other topics in occupational health.
Jill started her career as a research scientist by undertaking a PhD in the field of biophysical chemistry and immunochemistry at UBC in Vancouver, Canada. This was followed by postdoctoral experience at Harvard, USA studying the uptake of chemotherapeutic drugs. In 2001, after a long career break for family reasons, Jill took a position at the Centre for Cancer Epidemiology at the University of Manchester researching into models of acute stroke care delivery. In 2003 Jill was awarded a Daphne Jackson fellowship to study alkylation damage in sperm and the associations with male infertility at the Centre of Occupational and Environmental Health at the University of Manchester. Daphne Jackson Fellowships are specifically for scientists who have had a career break and the experience of returning to a career in science after being a full time parent has made Jill well aware of the difficulties for women in science, indeed it has shaped her career. Since her return to science Jill has developed a broad interest in epidemiology and has dozens of publications in a variety of fields. Nowadays Jill is never found in the lab but still remains a scientist at heart.
PhD University of British Columbia
MSc University of British Columbia
BSc (Hons) University of Reading
Collaborators and affiliated staff
- The modernet consortium
- Health and safety exceutive
- Health and safety laboratories
- University of Nottingham Medical School
- Cheraghi-Sohi, S., Singh, H., Reeves, D., Stocks, J., Rebecca, M., Esmail, A., ... Wet, C. D. (2016). Missed diagnostic opportunities and English general practice: a study to determine their incidence, confounding and contributing factors and potential impact on patients through retrospective review of electronic medical records. Implementation Science, 10(1). DOI:10.1186/s13012-015-0296-z. Publication link: 0afebbcc-0ca1-43fe-92ba-a469598f2113 | PubMed:26220545
- Montgomery, R., Stocks, S. J., & Wilkinson, S. M. (2016). Contact allergy resulting from the use of acrylate nails is increasing in both users and those who are occupationally exposed. Contact Dermatitis, 74(2), 120-122. DOI:10.1111/cod.12497. Publication link: 1ed75ce0-ce19-4f21-9235-b8259e82e166
- Stocks, S. J., Bensefa-Colas, L., & Berk, S. F. (2016). Worldwide trends in incidence in occupational allergy and asthma. Curr Opin Allergy Clin Immunol. DOI:10.1097/aci.0000000000000249. Publication link: f635ac8a-b927-4a5c-ae01-bc49d63d02c7
- Akbarov, A., Kontopantelis, E., Sperrin, M., Stocks, S. J., Williams, R., Rodgers, S., ... Ashcroft, D. M. (2015). Primary Care Medication Safety Surveillance with Integrated Primary and Secondary Care Electronic Health Records: A Cross-Sectional Study.Drug Safety, 38(7). DOI:10.1007/s40264-015-0304-x. Publication link: 21a7cb2e-f548-49f3-8b87-29ece6dda25d | PubMed:26100143
- Jarvis, J., Seed, M. J., Stocks, S. J., & Agius, R. M. (2015). A refined QSAR model for prediction of chemical asthma hazard.Occupational medicine (Oxford, England), 65(8). DOI:10.1093/occmed/kqv105. Publication link: d4d4ec98-b40a-47ab-94c4-3ef602ba4145 | PubMed:26209225
- Mcnamee, R., Stocks, S. J., McNamee, R., Turner, S., Carder, M., & Agius, R. M. (2015). The impact of national-level interventions to improve hygiene on the incidence of irritant contact dermatitis in healthcare workers: changes in incidence from 1996 to 2012 and interrupted times series analysis.The British journal of dermatology, 173(1). DOI:10.1111/bjd.13719. Publication link: 9b4ddaa7-605e-411a-b6fc-8443ba7ef226 | PubMed:25652874
- Stocks, S. J., Giles, S., Cheraghi-Sohi, S., & Campbell, S. (2015). Application of a tool for the evaluation of public and patient involvement in research. B M J Open, 5(3). DOI:10.1136/bmjopen-2014-006390. Publication link: 294241b1-aed4-4267-82ac-32107089e4aa | PubMed:25770228
- Stocks, S. J., Jones, K., Piney, M., & Agius, R. M. (2015). Isocyanate exposure and asthma in the UK vehicle repair industry.Occupational medicine (Oxford, England), 65(9). DOI:10.1093/occmed/kqv108. Publication link: 25fdc6fd-d84a-4389-b8ea-deefdc91ddc1 | PubMed:26209793
- Stocks, S. J., Kontopantelis, E., Akbarov, A., Rodgers, S., Avery, A. J., & Ashcroft, D. M. (2015). Examining variations in prescribing safety in UK general practice: cross sectional study using the Clinical Practice Research Datalink.BMJ (Clinical research ed.), 351. DOI:doi: 10.1136/bmj.h5501. Publication link: 420effa7-96dc-4c9d-b321-a9a563229137 | PubMed:26537416
- Stocks, S. J., McNamee, R., van der Molen, H. F., Paris, C., Urban, P., Campo, G., ... Agius, R. (2015). Trends in incidence of occupational asthma, contact dermatitis, noise-induced hearing loss, carpal tunnel syndrome and upper limb musculoskeletal disorders in European countries from 2000 to 2012.Occupational and environmental medicine, 72(4). DOI:10.1136/oemed-2014-102534. Publication link: f3c10ca5-895c-4280-9e75-a567ed635be7 | PubMed:25575531
- Bensefa-Colas, L., Telle-Lamberton, M., Paris, C., Faye, S., Stocks, S. J., Luc, A., ... Momas, I. (2014). Occupational allergic contact dermatitis and major allergens in France: temporal trends for the period 2001-2010.The British journal of dermatology, 171(6). DOI:10.1111/bjd.13133. Publication link: 91299378-96a3-4ef6-8cfc-3f6efa774165 | PubMed:24860919
- Povey, A. C., McNamee, R., Alhamwi, H., Stocks, S. J., Watkins, G., Burns, A., & Agius, R. (2014). Pesticide exposure and screen-positive neuropsychiatric disease in British sheep farmers.Environmental research, 135, 262-270. DOI:10.1016/j.envres.2014.09.008. Publication link: 3cb7bbbc-a77e-4092-ac17-5243b0b6f40d | PubMed:25462674
- Mcnamee, R., Stocks, S. J., McNamee, R., Turner, S., Carder, M., & Agius, R. M. (2013). Assessing the impact of national level interventions on workplace respiratory disease in the UK: part 1--changes in workplace exposure legislation and market forces.Occupational and environmental medicine, 70(7), 476-482. DOI:10.1136/oemed-2012-101123. Publication link: 08d2f6c5-8ee9-48f3-8232-b3ec1160f0a1 | PubMed:23596185
- Stocks, S. J., McNamee, R., Turner, S., Carder, M., & Agius, R. M. (2013). Assessing the impact of national level interventions on workplace respiratory disease in the UK: part 2--regulatory activity by the Health and Safety Executive.Occupational and environmental medicine, 70(7), 483-490. DOI:10.1136/oemed-2012-101124. Publication link: 6e7e1438-6b16-4999-afc1-15d716767839 | PubMed:23606324
- Enoch, S. J., Seed, M. J., Roberts, D. W., Cronin, M. T. D., Stocks, S. J., & Agius, R. M. (2012). Development of mechanism-based structural alerts for respiratory sensitization hazard identification. Chemical Research in Toxicology, 25(11), 2490-2498. DOI:10.1021/tx3003092. Publication link: 7464e46f-ccb4-451d-904c-88ee789df354 | PubMed:23057518
- Stocks, S. J., McNamee, R., Turner, S., Carder, M., & Agius, R. M. (2012). Has European Union legislation to reduce exposure to chromate in cement been effective in reducing the incidence of allergic contact dermatitis attributed to chromate in the UK?. Occupational and environmental medicine, 69(2), 150-152. DOI:10.1136/oemed-2011-100220. Publication link: 86bd5691-d919-438e-afad-cb3f14c5396d | PubMed:21849347
- Stocks, S. J., Turner, S., Mcnamee, R., Carder, M., Hussey, L., & Agius, R. M. (2011). Occupation and work-related ill-health in UK construction workers. Occupational Medicine, 61(6), 407-415. DOI:10.1093/occmed/kqr075. Publication link: 53b86ec6-997f-4867-b03f-984bdad46134 | PubMed:21752940
- Povey, A. C., & Stocks, S. J. (2010). Epidemiology and trends in male subfertility. Human Fertility, 13(4), 182-188. DOI:10.3109/14647273.2010.515700. Publication link: 4046cd44-f03a-43bc-b5ab-c6a21dd77bcf | PubMed:21117926
- Stocks, S. J., Agius, R. M., Cooley, N., Harrison, K. L., Brison, D. R., Horne, G., ... Povey, A. C. (2010). Alkylation of sperm DNA is associated with male factor infertility and a reduction in the proportion of oocytes fertilised during assisted reproduction. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 698(1-2), 18-23. DOI:10.1016/j.mrgentox.2010.02.019. Publication link: 6ca69a2f-8a9e-483e-8c31-18acf0e625b9 | PubMed:20307685
- Stocks, S. J., McNamee, R., Carder, M., & Agius, R. M. (2010). The incidence of medically reported work-related ill health in the UK construction industry. Occupational and Environmental Medicine, 67(8), 574-576. DOI:10.1136/oem.2009.053595. Publication link: 87e044cf-91cd-432e-8fc1-fc3bff45dc70 | PubMed:20647381
- Dey, P., Woodman, M., Gibbs, A., Steele, R., Stocks, S. J., Wagstaff, S., ... Chaudhuri, M. D. (2005). Early assessment by a mobile stroke team: A randomised controlled trial. Age and Ageing, 34(4), 331-338. DOI:10.1093/ageing/afi102. Publication link: f51b71ae-d3da-4915-914c-5ce861d073d4 | PubMed:15955756
- Gerweck, L. E., Kozin, S. V., & Stocks, S. J. (1999). The pH partition theory predicts the accumulation and toxicity of doxorubicin in normal and low-pH-adapted cells. British Journal of Cancer, 79(5-6), 838-842. DOI:10.1038/sj.bjc.6690134. Publication link: 1c0cccc8-7603-4a97-aef2-2322db0d39de | PubMed:10070878
- Brooks, D. E., & Stocks, S. J. (1994). Use of polyacrylamide-derivatized antibody in dextran-poly(ethylene glycol) systems. Methods in Enzymology, 228, 390-395. DOI:10.1016/0076-6879(94)28038-X. Publication link: c5fa9c8c-7edd-46d7-9c08-6a3c35be8f4c | PubMed:7519294
- Stocks, S. J., & Brooks, D. E. (1989). Production and isolation of large quantities of monoclonal antibody using serum-free medium and fast protein liquid chromatography. Hybridoma, 8(2), 241-247.. Publication link: e4cb78c7-be9c-4323-92bf-3306d89a6231 | PubMed:2714816
- Stocks, J., Stocks, S. J., & Brooks, D. E. (1988). Development of a general ligand for immunoaffinity partitioning in two phase aqueous polymer systems. Analytical Biochemistry, 173(1), 86-92.. Publication link: 7a5a129f-8758-46e4-883b-cc5560955653 | PubMed:2461120